Abstract and keywords
Abstract (English):
The aim of this work was to test the technology of treatment of malignant tumors "Karanahan" on the Lewis lung carcinoma model and to prove the existence of the third antitumor therapeutic vector of this technology – activation of antitumor immunity.

Keywords:
“Karanahan” technology, stem tumor cells, cross-linking cytostatic, composite dsDNA preparation, reparative cycle, cell cycle, dissemination of stem tumor cells, antitumor immune response, repolarization of tumor-associated strom
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References

1. Chronometric Administration of Cyclophosphamide and a Double-Stranded DNA-Mix atInterstrand Crosslinks Repair Timing, Called “Karanahan” Therapy, Is Highly Efficient in a Weakly Immunogenic Lewis Carcinoma Model / V. Ruzanova [et al.] // Pathology and Oncology Research. - 2022. - Vol.28, № 1610180.

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