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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Foods and Raw Materials</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Foods and Raw Materials</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Foods and Raw Materials</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2308-4057</issn>
   <issn publication-format="online">2310-9599</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">27038</article-id>
   <article-id pub-id-type="doi">10.21179/2308-4057-2016-2-66-74</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>FOOD PRODUCTION TECHNOLOGY </subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>FOOD PRODUCTION TECHNOLOGY </subject>
    </subj-group>
    <subj-group>
     <subject>FOOD PRODUCTION TECHNOLOGY </subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">METHODOLOGICAL ASPECTS AND OPERATIONAL EXPERIENCE OF THE NEW BAA WITH TARGETED FUNCTIONAL PROPERTIES</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>METHODOLOGICAL ASPECTS AND OPERATIONAL EXPERIENCE OF THE NEW BAA WITH TARGETED FUNCTIONAL PROPERTIES</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Lobach</surname>
       <given-names>E Yu</given-names>
      </name>
      <name xml:lang="en">
       <surname>Lobach</surname>
       <given-names>E Yu</given-names>
      </name>
     </name-alternatives>
     <email>lobach_evgenia@mail.ru</email>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Poznyakovskiy</surname>
       <given-names>V M</given-names>
      </name>
      <name xml:lang="en">
       <surname>Poznyakovskiy</surname>
       <given-names>V M</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Kemerovo Institute of Food Science and Technology (University)</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">Kemerovo Institute of Food Science and Technology (University)</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">South Ural State University (National Research University)</institution>
     <country>ru</country>
    </aff>
    <aff>
     <institution xml:lang="en">South Ural State University (National Research University)</institution>
     <country>ru</country>
    </aff>
   </aff-alternatives>
   <volume>4</volume>
   <issue>2</issue>
   <fpage>66</fpage>
   <lpage>74</lpage>
   <self-uri xlink:href="https://jsocnet.ru/en/nauka/article/27038/view">https://jsocnet.ru/en/nauka/article/27038/view</self-uri>
   <abstract xml:lang="ru">
    <p>Specialized food products development, including biologically active additives (BAA), is one of the priority areas in the realization of the healthy eating program and the food and pharmaceutical industries development in the Russian Federation. A lot of attention is paid to the proof of effectiveness and functional orientation of the concerned foodstuff. Dietetic therapy with the use of BAA is considered to be the most available way to improve the modern man’s nutrition and health. The aim of this work was to develop and confirm specialized food products’ practical application through clinical trials and mass production organization. Specialized products for dietetic nutrition and protective diet such as BAA (“Energopan”, “Cleopanta”, “Green Star”) and the “Light mood” bar were developed. Methodological aspects of the new types of the specialized products’ creation were described. Prescription formulas with account taken of pharmacological characteristics of their active principles were scientifically proven. Regulated indices of nutrition value including recommended amount of consumption of the developed product and safety criteria that allowed establishing duration of realization were identified. Clinical trials of the specialized products were conducted: “Light mood” bar and the BAA “Green Star” were included in study groups’ ration and their biomedical measurements characterizing metabolic care were analyzed. Observational results allowed to recommend the “Light mood” bar for prophylaxis and treatment of the constipation in combination with other somatic diseases and the BAA “Green Star” for digestion health improvement in the function of energy absorbent and improvement of the overall level of metabolism. Developed products’ formulation and technology were tested under production conditions in the SPA “Yug” and the “Art-Life” company (Russia).</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Specialized food products development, including biologically active additives (BAA), is one of the priority areas in the realization of the healthy eating program and the food and pharmaceutical industries development in the Russian Federation. A lot of attention is paid to the proof of effectiveness and functional orientation of the concerned foodstuff. Dietetic therapy with the use of BAA is considered to be the most available way to improve the modern man’s nutrition and health. The aim of this work was to develop and confirm specialized food products’ practical application through clinical trials and mass production organization. Specialized products for dietetic nutrition and protective diet such as BAA (“Energopan”, “Cleopanta”, “Green Star”) and the “Light mood” bar were developed. Methodological aspects of the new types of the specialized products’ creation were described. Prescription formulas with account taken of pharmacological characteristics of their active principles were scientifically proven. Regulated indices of nutrition value including recommended amount of consumption of the developed product and safety criteria that allowed establishing duration of realization were identified. Clinical trials of the specialized products were conducted: “Light mood” bar and the BAA “Green Star” were included in study groups’ ration and their biomedical measurements characterizing metabolic care were analyzed. Observational results allowed to recommend the “Light mood” bar for prophylaxis and treatment of the constipation in combination with other somatic diseases and the BAA “Green Star” for digestion health improvement in the function of energy absorbent and improvement of the overall level of metabolism. Developed products’ formulation and technology were tested under production conditions in the SPA “Yug” and the “Art-Life” company (Russia).</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>prescription ingredients</kwd>
    <kwd>biologically active additives</kwd>
    <kwd>functional properties</kwd>
    <kwd>effectiveness</kwd>
    <kwd>clinical trials</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>prescription ingredients</kwd>
    <kwd>biologically active additives</kwd>
    <kwd>functional properties</kwd>
    <kwd>effectiveness</kwd>
    <kwd>clinical trials</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p>INTRODUCTION Nutrition is one of the most important factors determining the health of the population. Healthy eating helps to prevent diseases, to prolong life, to improve working capacity, to enable adaption to environmental conditions. At the same time there are negative trends in the health status of the population. The majority has nutrition disorders due to both poor nutrient materials intake, especially vitamins, macro- and micronutrients, and complete proteins, as well as their irrational ratio. There is every reason to believe that the most rapid, economical and scientifically grounded way to solve the nutrition rationalization problem is the widespread use of specialized products, including BAA [12, 14]. The RAND Corporation presented the results of the evaluation of the world community science and technology and social and economic development prospects for the period until 2020, including “challenge-response” mechanism. The driving forces of the modern innovation process and obstacles on its way and various scientific and technological development priorities were analyzed. Among the latter the main attention is given to healthy lifestyle and ultimate nutrition ensuring and prevention of common conditions of the infectious and nutritional (non-infectious) nature. In relation to this trend the great importance have development issues of specialized products, including BAA, study of the composition, pharmacologic orientation and functional properties of starting materials. They are determined by science and technology priorities of the modern nutritiology. Also the importance is given to the efficiency evidence and functional orientation of the concerned food products by conducting clinical trials. In such case dietetic therapy is considered to be the most available way to improve the modern man’s nutrition and health [13, 15, 20]. OBJECTS AND METHODS OF STUDY The objects of research were starting materials used in development of prescription formulae for the new BAA types such as “Energopan”, ‘Cleopanta”, “Green Star”, “Light mood” bar, and their laboratory and industrial samples. Standard and special methods of quality and safety research of the developed products were used with the help of spectophotometery, stripping voltammetry, and liquid chromatography. Tests were carried out on the basis of accredited laboratories of the SPA “Yug” (Biysk, Russia) and “Art-life” company (Tomsk, Russia). For the “Cleopanta” identification the panto-hematogen authenticity was conducted according to the developed technique. 10 ml of Feling reagent are added to a solution of 0.2 g of the capsule contents in 5 ml of the water and brought to boil. Glucose flocculates in russet. The resulting solution is put to test according to GOST (All Union State Standars) 30418-96 to isolate triglycerides’ fatty acid composition that occurs in plasma lipoproteins. The content of pantohematogen is determined spectrophotometrically by the level of hemoglobin at a wavelength of 540 nm. About 0.8 g of the capsule contents is placed in a mortar, then 5 ml of 0.5% aqueous ammonia solution are added and everything is pestled until dissolved. The solution is quantitatively transferred to a 50 ml volumetric flask with wash of 0.5% ammonia solution (10 ml three times). The resulting solution is kept at room temperature in a shadowed place with intermittent mixing for an hour and filtered through cheesecloth or cotton plug, the filter is washed with 0.5% ammonia solution to bring the total filtrate volume to 50 ml. The optical density of the solution is measured on a spectrophotometer at a wavelength of 540 nm in a cuvette with 10 mm layer thickness by using the 0.5% ammonia solution as a blank solution. The optical density should be at least 0.4. The data obtained from examination and monitoring of 30 patients with functional constipation of the 1-2 type was used when clinical trials of the “Light mood” bar were conducted. The diagnosis of functional constipation was made by a gastroenterologist after patients’ cohort study on the basis of historical studies, results of physical examination, laboratory and instrumental methods of research as well as test results of diagnosing the quality of life over time during treatment. Patients with FC were given 1-2 “Light mood” bars for 15 days before bedtime. Differences between parameters of comparison were considered statistically dissimilar at P</p>
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