<!DOCTYPE article
PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20190208//EN"
       "JATS-journalpublishing1.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.4" xml:lang="en">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Dairy industry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Dairy industry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Молочная промышленность</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">1019-8946</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">70652</article-id>
   <article-id pub-id-type="doi">10.21603/1019-8946-2023-5-16</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Статья</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>ARTICLE</subject>
    </subj-group>
    <subj-group>
     <subject>Статья</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">Effect of Lactobacillus acidophilus on biofilm growth in cheese whey</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Влияние Lactobacillus acidophilus на рост биопленок в подсырной сыворотке</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Рябцева</surname>
       <given-names>Светлана Андреевна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Ryabtseva</surname>
       <given-names>S. A.</given-names>
      </name>
     </name-alternatives>
     <email>ryabtseva07@mail.ru</email>
     <bio xml:lang="ru">
      <p>доктор технических наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>doctor of technical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Брежнева</surname>
       <given-names>Юлия Александровна</given-names>
      </name>
      <name xml:lang="en">
       <surname>Brezhneva</surname>
       <given-names>Yu. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Анисимов</surname>
       <given-names>Георгий Сергеевич </given-names>
      </name>
      <name xml:lang="en">
       <surname>Anisimov</surname>
       <given-names>George S </given-names>
      </name>
     </name-alternatives>
     <bio xml:lang="ru">
      <p>кандидат технических наук;</p>
     </bio>
     <bio xml:lang="en">
      <p>candidate of technical sciences;</p>
     </bio>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Северо-Кавказский федеральный университет</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">North-Caucasus Federal University</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Северо-Кавказский федеральный университет</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">North-Caucasus Federal University</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Северо-Кавказский федеральный университет</institution>
     <city>Ставрополь</city>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">North Caucasus Federal University</institution>
     <city>Stavropol</city>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2023-10-10T00:00:00+03:00">
    <day>10</day>
    <month>10</month>
    <year>2023</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2023-10-10T00:00:00+03:00">
    <day>10</day>
    <month>10</month>
    <year>2023</year>
   </pub-date>
   <issue>5</issue>
   <fpage>36</fpage>
   <lpage>37</lpage>
   <history>
    <date date-type="received" iso-8601-date="2023-09-05T00:00:00+03:00">
     <day>05</day>
     <month>09</month>
     <year>2023</year>
    </date>
   </history>
   <self-uri xlink:href="https://moloprom.kemsu.ru/en/nauka/article/70652/view">https://moloprom.kemsu.ru/en/nauka/article/70652/view</self-uri>
   <abstract xml:lang="ru">
    <p>Проведено моделирование образования биопленок в подсырной сыворотке на стекле в статических условиях, в том числе с участием Lactobacillus acidophilus. Биопленки развивались быстрее в подсырной сыворотке, нежели в пермеате, полученном методом ультрафильтрации. Основу трехмерной структуры зрелой биопленки составили представители родов, входящих в группу санитарно-показательных микроорганизмов. Дрожжи участвовали во всех этапах формирования биопленок. Клетки L. acidophilus закваски «БК-Углич-АВ» активно встраивались в структуру биопленки, подавляя рост грамотрицательных бактерий и способствуя разрушению экзополисахаридного слоя, но не влияя на дрожжи. Полученные данные можно использовать как для разработки методов контроля биопленок в молочной промышленности, так и для биотехнологических целей.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>The modeling of the biofilms formation in cheese whey on glass under static conditions including with Lactobacillus acidophilus was carried out. Biofilm development in cheese whey is faster than in its ultrafiltration permeate. The basis of the three-dimensional structure of a mature biofilm is made up of representatives of the genera included in the group of sanitary indicative microorganisms. Yeasts are involved in all stages of biofilm formation. L. acidophilus cells of the «BK-Uglich-AV» starter actively integrate into the biofilm structure, inhibiting the growth of gram-negative bacteria and contributing to the destruction of the exopolysaccharide layer, but without affecting yeast. The data obtained can be used both for the development of biofilm control methods in the dairy industry and for biotechnological purposes.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>биопленки</kwd>
    <kwd>формирование</kwd>
    <kwd>подсырная сыворотка</kwd>
    <kwd>Lactobacillus acidophilus.</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>biofilms</kwd>
    <kwd>formation</kwd>
    <kwd>cheese whey</kwd>
    <kwd>Lactobacillus acidophilus</kwd>
   </kwd-group>
   <funding-group>
    <funding-statement xml:lang="ru">Работа выполнена при финансовой поддержке Министерства науки и высшего образования Российской Федерации в рамках реализации комплексного проекта по созданию высокотехнологичного производства по теме «Создание первого в России высокотехнологичного производства пребиотика лактулозы и функциональных молочных ингредиентов для импортозамещения в медицине, ветеринарии, детском питании, производстве лечебно-профилактических продуктов для людей и животных» (Соглашение № 075-11- 2022-021 от 07.04.2022 г.).</funding-statement>
   </funding-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Рябцева, С. А. Биопленки в молочной промышленности: значение, формирование, контроль / С. А. Рябцева [и др.]// Молочная промышленность. 2018. № 1. С. 57-59.</mixed-citation>
     <mixed-citation xml:lang="en">Ryabceva, S. A. Bioplenki v molochnoy promyshlennosti: znachenie, formirovanie, kontrol' / S. A. Ryabceva [i dr.]// Molochnaya promyshlennost'. 2018. № 1. S. 57-59.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Barzegari, A. The battle of probiotics and their derivatives against biofilms / A. Barzegari [et al.]// Infection and drug resistance. 2020. V. 13. P. 659-672. DOI:10.2147 / IDR. S232982</mixed-citation>
     <mixed-citation xml:lang="en">Barzegari, A. The battle of probiotics and their derivatives against biofilms / A. Barzegari [et al.]// Infection and drug resistance. 2020. V. 13. P. 659-672. DOI:10.2147 / IDR. S232982</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Fang, K. Controlling biofilms using synthetic biology approaches / K. Fang, O. J. Park, S. H. Hong// Biotechnology Advances. 2020. V. 40. P. 107518. doi: 10.1016 / j.biotechadv.2020.107518</mixed-citation>
     <mixed-citation xml:lang="en">Fang, K. Controlling biofilms using synthetic biology approaches / K. Fang, O. J. Park, S. H. Hong// Biotechnology Advances. 2020. V. 40. P. 107518. doi: 10.1016 / j.biotechadv.2020.107518</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Berlanga, M. Living together in biofilms: the microbial cell factory and its biotechnological implications / M. Berlanga, R. Guerrero// Microbial Cell Factories. 2016. V. 15. P. 165. https://doi.org / 10.1186 / s12934-016-0569-5</mixed-citation>
     <mixed-citation xml:lang="en">Berlanga, M. Living together in biofilms: the microbial cell factory and its biotechnological implications / M. Berlanga, R. Guerrero// Microbial Cell Factories. 2016. V. 15. P. 165. https://doi.org / 10.1186 / s12934-016-0569-5</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Wang, M. Lactulose production from lactose isomerization by chemocatalysts and enzymes: Current status and future perspectives / M. Wang [et al.]// Biotechnology Advances. 2022. Р. 108021. doi: 10.1016 / j. biotechadv. 2022.108021</mixed-citation>
     <mixed-citation xml:lang="en">Wang, M. Lactulose production from lactose isomerization by chemocatalysts and enzymes: Current status and future perspectives / M. Wang [et al.]// Biotechnology Advances. 2022. R. 108021. doi: 10.1016 / j. biotechadv. 2022.108021</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Ryabtseva, S. A. Modelling biofilms formation and removal in secondary dairy raw materials / S. A. Ryabtseva [et al.]// Foods and Raw Materials. 2021. V. 9 (1). P. 59-68. https://doi.org / 10.21603 / 2308-4057-2021-1-59-68</mixed-citation>
     <mixed-citation xml:lang="en">Ryabtseva, S. A. Modelling biofilms formation and removal in secondary dairy raw materials / S. A. Ryabtseva [et al.]// Foods and Raw Materials. 2021. V. 9 (1). P. 59-68. https://doi.org / 10.21603 / 2308-4057-2021-1-59-68</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Marka, S. Feed substrates influence biofilm formation on reverse osmosis membranes and their cleaning efficiency / S. Marka, S. Anand//Journal of Dairy Science. 2017. V. 101. Р. 1-12.</mixed-citation>
     <mixed-citation xml:lang="en">Marka, S. Feed substrates influence biofilm formation on reverse osmosis membranes and their cleaning efficiency / S. Marka, S. Anand//Journal of Dairy Science. 2017. V. 101. R. 1-12.</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
