The article is devoted to a research of historical, cultural and natural heritage of biologists of the Kemerovo State University, their contribution to solving environmental problems of the region, to preservation of the plant and animal life of Kuzbass by creating natural reserves and designated conservation areas in Kuzbass. the results of long-term scientifi research conducted by local biologists were included into Inventories of the rare and protected animals and plants which formed the basis of the Red Lists of the Kemerovo region. The article features the role of the Siberian Archeology, Ethnography and Ecology Museum (KemSU) in preservation of regional natural heritage and ecological awareness promotion among school and university students. On the basis of museum materials, it traces the history of scientifi research connected with environmental protection. The environmental exhibit of the museum displays items of natural biodiversity of the Kemerovo region and Siberia which entered the zoological, entomological, theriological, ornithological collections and materials presenting the ecological situation in the area. These collections are sources for scientifi research in biology, zoology, geology and ecology.