Dairy industry Dairy industry Молочная промышленность 1019-8946 105698 10.21603/1019-8946-2025-5-60 Обзорная статья Review article Обзорная статья Antiphage Efficiency of Biocides at Dairy Plants Противофаговая эффективность биоцидов, применяемых на молочных заводах Полянская Ирина Сергеевна Polyanskaya Irina S. poljanska69@mail.ru

кандидат технических наук;

candidate of technical sciences;

 Вологодская государственная молочнохозяйственная академия имени Н. В. Верещагина Молочное Россия Vologda State Dairy Farming Academy Molochnoye Russian Federation 21 10 2025 21 10 2025 5 44 58 03 03 2025 19 09 2025 https://moloprom.kemsu.ru/en/nauka/article/105698/view

Фаголизис заквасочной микробиоты при производстве ферментированных молочных продуктов представляет собой серьезную угрозу безопасности и качеству продукции. Сведения о вирулицидной активности коммерческих дезинфицирующих веществ, предназначенных для молочной промышленности, более ограниченны по сравнению с антибактериальной активностью, и требуют своей актуализации в свете разработки эффективных процедур инактивации фагов на молочных заводах, программ нормального и усиленного режимов мойки и дезинфекции на конкретном предприятии против появляющихся новых устойчивых фагов. Подходы и выбор ротации биоцидов, включая фагодиагностику, исследования бактериофагов различных видов молочнокислых бактерий, также имеют важное значение для разработки более эффективных процедур инактивации фагов в лабораториях. Цель литературного обзора – выявление возможности направленных профилактических противофаговых дезинфекционных мероприятий на молокоперерабатывающем заводе для дальнейшей разработки инструкции по санитарной обработке на предприятиях молочной промышленности. Анализ оригинальных и обзорных статей на русском и английском языках был осуществлен с применением ресурсов электронных библиотек и поисковых систем eLIBRARY.RU, CyberLeninka, Schoolar Google, Science Direct, PubMed. Выявлено, что, несмотря на значительный прогресс в области изучения вирулицидной активности дезинфицирующих средств, остаются нерешенные вопросы, связанные с тщательным и регулярным изучением доступных биоцидов против появляющихся новых фагов, с использованием системы ротации биоцидов на конкретных предприятиях. Полученные данные могут быть использованы при разработке направленных профилактических противофаговых мероприятий на молокоперерабатывающих заводах, при пересмотре санитарных правил для предприятий молочной промышленности, разработке инструкции по санитарной обработке технологического оборудования и производственных помещений на предприятиях молочной промышленности, а также санитарных правил для исследовательских лабораторий, работающих с бактериофагами молочнокислых бактерий.

The phagolysis of starter microbiota poses a serious threat to dairy safety and quality. Virucidal activity of commercial disinfectants in the dairy industry remains a less popular topic than their antibacterial activity. New effective phage inactivation procedures require new procedures for normal and enhanced disinfection. New biocide rotation selection methods include phage diagnostics and studies of various lactic acid bacteria bacteriophages. They also make it possible to develop more effective phage inactivation procedures for scientific laboratories. This review focuses on the feasibility of targeted preventive antiphage disinfection measures to develop new sanitization procedures for dairy plants and laboratories. The review covered articles in Russian and English registered in eLIBRARY.RU, CyberLeninka, Schoolar Google, Science Direct, and PubMed. Regarding the virucidal activity of disinfectants, the unresolved issues include evaluation of available biocides against new phages, as well as using a biocide rotation system at specific facilities. The data obtained can be used to develop targeted preventive antiphage measures in the dairy industry, to revise sanitary standards, to develop new sanitization procedures, and to design new sanitary regulations for research laboratories that work with lactic acid bacteria bacteriophages.

 Молочные продукты молочнокислые бактерии бактериофаги биоциды дезинфекция надуксусная кислота четвертичные аммониевые соединения поливинилпирролидон-йод УФ-обработка dairy products lactic acid bacteria bacteriophages biocides disinfection peracetic acid quaternary ammonium compounds polyvinylpyrrolidone iodine UV treatment

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